Take the "awful writers who will never get published" out of the equation first. Given that your book is indeed good, I truly believe that the more you submit, the better your chances of finding the right agent or publisher.
Every one of my rejection helped me move forward toward acceptance. Either I improved my queries, or updated my ms. based on repeated suggestions, or I learned to target the market better. Also, it made my skin so much thicker. By the time I accumulated 25 rejections, I was submitting like clockwork, efficient and without any kind of "oh geez, they really don't like me" self-doubt. I also learned to look for the right agents and check all the guidelines. By rejection #40 I was a lean, mean submission machine. And by rejection #65, I got accepted.
It could happen to you.